phosphorylated p egfr tyr992 (Cell Signaling Technology Inc)
Structured Review

Phosphorylated P Egfr Tyr992, supplied by Cell Signaling Technology Inc, used in various techniques. Bioz Stars score: 95/100, based on 188 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/phosphorylated p egfr tyr992/product/Cell Signaling Technology Inc
Average 95 stars, based on 188 article reviews
Images
1) Product Images from "The Combination of Gefitinib With ATRA and ATO Induces Myeloid Differentiation in Acute Promyelocytic Leukemia Resistant Cells"
Article Title: The Combination of Gefitinib With ATRA and ATO Induces Myeloid Differentiation in Acute Promyelocytic Leukemia Resistant Cells
Journal: Frontiers in Oncology
doi: 10.3389/fonc.2021.686445
Figure Legend Snippet: EGFR, p-EGFR (Tyr992), SYK, EGF, and AREG protein expression in APL patient samples. (A) Western blotting analysis of EGFR, p-EGFR (Tyr992), SYK, and β-actin protein levels in CD34 + cells isolated from normal BM of one healthy adult volunteer and 10 representative primary APL samples collected at diagnosis. HeLa cells served as a positive control to assess EGFR and p-EGFR (Tyr992) expression, and MV4-11 cell extracts were used as a positive control for SYK expression. EGFR and p-EGFR (Tyr992) were detectable when exposed for 180 seconds (sec). (B) EGF levels in BM plasma samples from healthy donors (n=15) and APL patients at diagnosis (n=16). (C) Plasma AREG levels in BM from healthy donors (n=20) and APL patients at diagnosis (n=17). (**) p < 0.01 (Mann-Whitney U-test).
Techniques Used: Expressing, Western Blot, Isolation, Biomarker Discovery, Positive Control, Clinical Proteomics, MANN-WHITNEY